Global Burden of Disease Study

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A horizontal bar chart titled “Headaches Cause More Harm in Women.” The chart shows age-standardized years lived with disability (YLDs) per 100,000 people in 2023, comparing women (dark blue) and men (yellow). For all headache disorders, women experience roughly twice the YLDs of men. The gap is larger for migraine, with women showing substantially higher disability than men. For tension-type headache, disability levels are much lower overall but remain higher in women than men. Source: IHME; chart by CFR/Allison Krugman for Think Global Health.

Why 1 in 3 People Worldwide Suffer From Headaches

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Pain medication misuse can stem from inadequate awareness around the global burden of headaches

Six small line charts show global disease burden trends, measured in disability-adjusted life-years (DALYs) per 100,000 people, from 2000 to 2023. The top row—diarrheal diseases, HIV/AIDS, and tuberculosis—shows steady declines. A vertical line in 2020 marks the COVID-19 pandemic. The bottom row—ischemic heart disease, diabetes mellitus, and depressive disorders—shows ischemic heart disease remaining high with slight fluctuation, while diabetes and depression rise modestly. Infectious diseases fall sharply as noncommunicable diseases rise.

Around the World, Chronic Diseases Are Rising

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A new iteration of the Global Burden of Disease Study charts how 25 leading health risks have improved or worsened

Using AI to Track Gender-Based Violence

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Artificial intelligence allows safe GBV monitoring and reporting in low- or middle-income countries where data is scarce

Using AI to Track Gender-Based Violence

India's Call for Action on Noncommunicable Diseases

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Noncommunicable diseases cause the majority of deaths in India, but public health responses fall short

India's Call for Action on Noncommunicable Diseases

Inside the Global Burden of Disease Study

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IHME Director Christopher Murray recounts the study's role in shaping global policy and how collaborators overcame COVID

Inside the Global Burden of Disease Study

How Gender and Sex Shape Disease

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New research exposes why health systems should tailor responses to the needs of men and women starting at a young age

How Gender and Sex Shape Disease

Global Fertility Rate Continues To Fall: How Governments Could Prepare

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The global fertility rate will decline from now through 2100, according to new projections in The Lancet

Global Fertility Rate Continues To Fall: How Governments Could Prepare

Global Life Expectancy Declines for First Time in 30 Years

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Overall life expectancy is struggling, according to a highly anticipated update to the Global Burden of Disease study

Global Life Expectancy Declines for First Time in 30 Years

Tackling the World's Most Vexing Diseases Through Data

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A call to re-shape the way policymakers make health decisions by getting the most cost-effective priorities straight

Students wear face masks during a health-care action rally dedicated to COVID-19 in Solo, Central Java, Indonesia on February 3, 2020

Diabetes and TB—A Complicating Combo

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Though they are entirely different types of diseases TB and diabetes exacerbate each other in surprising—and costly—ways

A health technician analyses blood samples for tuberculosis testing in a high-tech TB laboratory in Carabayllo, an area in Lima, Peru on May 19, 2016. The image shows a splashing liquid being washed across glass plates each of which is dotted with what appears to be a blood drop sample. REUTERS/Mariana Bazo

Age Ain't Nothing but a Number—Except When it Comes to Health

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In some parts of the world, forty is the new seventy

An elderly demonstrator poses for the camera as he makes a V-sign during ongoing anti-government protests, in Baghdad, Iraq, December 10, 2019. He has a black-and-white checkered scarf tied on his head and a red and white sash with green accents, around his neck. He has a very long white beard and friendly eyes. REUTERS/Alaa al-MarjaniSELECT

How to Prevent a Million Children's Deaths

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Closing gap on child mortality for UN Sustainable Development Goal 3.2 in ten years may take baby steps, not giant leaps

Children play in water pipes at a construction site on the banks of the Yamuna River on July 26, 2010in the northern Indian city of Allahabad. Picture shows several rows of large, concrete sewer pipes stacked on top of each other with their fat openings facing the camera. Each is large enough to fit one child huddled at the opening. About ten children can be seen climbing about on the feature. REUTERS/Jitendra Prakash