Late or missed diagnoses remain one of the most obstinate causes of preventable deaths in Africa. Each year, treatable conditions including tuberculosis, cervical cancer, and certain noncommunicable diseases (NCDs) kill millions of people across the continent. But treatment is not the main barrier.

What is missing is timely, reliable, and affordable diagnosis. For decades, partnerships with the United States, European countries such as France and Germany, and multilateral agencies have tried to address those gaps in Africa. In recent years, another actor has joined the effort: Singapore. 

Better known as a global hub for trade and finance, Singapore has built one of Asia's most advanced diagnostic systems for detecting disease. Those applications are now beginning to resonate thousands of miles away, in collaboration with African governments, hospitals, and innovators. In Singapore, artificial intelligence (AI) is increasingly powering diagnostic tools by enabling faster disease detection, predictive analytics, and more equitable access to care in resource-limited settings. As of late 2024, Singapore's government agreed to pledge up to $200 million to the island's public health institutions for the use of AI to improve patient care.  

At its core, Singapore's engagement with Africa is reciprocal learning. African partners gain from Singapore's regulatory expertise, system integration, and innovation ecosystem. Singaporean institutions learn from Africa's models of scale, frugality, and community-based health care. 

Africa is not a single story—its 54 countries are a patchwork of health systems, regulatory environments, and innovation ecosystems. That diversity makes Africa a dynamic partner—one that is cocreating approaches to diagnostics that neither its nations nor Singapore could have developed alone. 

Investments in diagnostics have been overshadowed historically by investments in vaccines, drugs, and health financing. The COVID-19 pandemic changed that calculus, exposing just how fragile testing and surveillance systems were worldwide. 

Singapore had spent decades investing early in laboratory capacity, regulatory science, and digital health data. Because of that preparation, the country was able to expand testing quickly when the pandemic struck. That capability is now shaping a new phase of its international partnerships, especially in Africa, where diagnostic bottlenecks remain acute. 

For African governments, Singapore's story resonates because it is a small state that has transformed constraint into capacity. For Singapore, Africa is not only a frontier market but also a place where innovations can be stress-tested at scale. 

Turning the Tide of Tuberculosis 

Tuberculosis remains one of Africa's deadliest diseases, claiming more than 400,000 lives annually. The central challenge is not treatment but timely diagnosis. Across much of the continent, chest X-rays and sputum tests are often delayed because of shortages of equipment and radiologists. That results in patients going undetected until the disease has advanced or been transmitted. 

Singapore's national healthtech agency, Synapxe—which first trialed AI-assisted chest X-ray tools in its National Tuberculosis Screening Centre—could consider future collaboration with hospitals in Ghana, Kenya, and Nigeria, where similar tools have been trialed by other players, as a means to adapt and scale these techniques for African use. In Ethiopia, AI-assisted X-ray screenings identified subtle lung lesions that might have otherwise gone undiagnosed, helping detect TB incidence rates in 8.5% of those screened—nearly seven times the national average. 

Singapore has strengthened the enabling environment beyond technology alone. Singapore's Health Sciences Authority, long regarded for its regulatory science expertise in medical devices and AI diagnostics, has become a reference point for officials worldwide. Although formal collaborations in Africa are still emerging, exchanges through global platforms such as the International Coalition of Medicines Regulatory Authorities and the World Health Organization (WHO) are informing how African regulators approach the clinical validation of AI tools. This cross-learning is gradually helping build confidence that new diagnostic technologies can meet international standards while being adapted for local use. 

At the same time, Singapore's strengths in financing and investment are beginning to find footholds in African healthtech. Rather than focusing solely on donor-driven procurement, Singapore-based funds have backed startups such as Helium Health in Nigeria, which digitizes hospital and diagnostic records, and mPharma in Ghana, which manages community pharmacies and supply chains to improve access to medicines and diagnostic services. 

These types of investments demonstrate how Singapore's capital and system design experience can complement Africa's entrepreneurial drive to build sustainable models for health-care delivery. TB diagnostics remain heavily supported by the Global Fund and Unitaid, but the growing involvement of Singaporean investors in broader healthtech signals an opportunity: embedding innovations into domestic budgets and private sector ecosystems so that access does not depend solely on external aid. 

Taken together, such partnerships highlight how Singapore's combined strengths in regulation, financing, and innovation can support Africa's push for faster, more equitable, and ultimately sovereign health systems. 

Cervical Cancer: Screening Access as System Equity

Singaporean startups and Singapore-backed firms have also begun piloting smartphone-based cervical cancer screening tools in East Africa. Cervical cancer is the fourth most common cancer among women worldwide, and in sub-Saharan Africa remains the leading cause of cancer-related deaths. According to the WHO, more than 85% of cervical cancer deaths occur in low- and middle-income countries, Africa carrying the heaviest burden. As true of TB, the primary challenge is not treatment but late or missed diagnoses, which prevent women from accessing care when it is most effective. 

In Rwanda, Singapore-backed medtech firms such as MobileODT have partnered with local hospitals to expand cervical cancer screening. MobileODT's flagship technology, the EVA System, is a smartphone-linked colposcope that allows nurses to capture high-quality images of the cervix and upload them securely for cloud-based analysis. By leveraging portable devices rather than complex laboratory infrastructure, this technology enables screenings to be performed in rural clinics and results available almost instantly. 

The pilots have proven to have an impact in settings where access to gynecologists and diagnostic labs is scarce. Nurses trained to use the EVA System can detect precancerous changes early and refer patients before the disease advances [PDF]. In Rwanda alone, 5,000 women between 30 and 54 were screened with this tool. In addition to shortening the diagnostic timeline and expanding access to care, the EVA system reduces the risk of women's being lost to follow-up—a recurring challenge in cancer care across low-resource settings. 

More broadly, this system reflects Singapore's broader ethos of lean, high-quality engineering: devices that are efficient, portable, and designed to withstand real-world constraints. In African contexts, those qualities are more than design choices—they are lifelines. By embedding such technologies into primary care, Singaporean-backed innovation is extending diagnostic access to women who have historically been left out, even as Singapore learns from African partners how to build solutions that are scalable, resilient, and culturally grounded. 

Noncommunicable Diseases: The Next Diagnostic Frontier 

As Africa undergoes an epidemiological transition, NCDs are swiftly rising alongside infectious threats. Diabetes is among the most pressing: An estimated 24 million [PDF] Africans live with diabetes, a number expected to swell to 55 million by 2045. As prevalence climbs in both urban and rural parts of Africa, one complication in particular presents a challenge. Diabetic retinopathy is now a leading cause of preventable blindness, primarily because early detection remains rare. Again, the obstacle is not lack of treatment but the absence of timely and accessible screening, which is essential for preserving sight.